The Pickart 2018 review documented effects on collagen synthesis, anti-inflammatory signaling, nerve regeneration, and stem cell recruitment (Pickart et al., Int J Mol Sci, 2018)
The choice depends on the patients health and needs, like bleeding disorders or frequent injections
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This is clinically relevant because obesity itself is associated with numerous health conditions that might influence treatment tolerance, including metabolic syndrome, cardiovascular disease, sleep apnea, and hepatic steatosis
Severe cases of b12 overdose level may cause high blood pressure or heart palpitations